Year 2015,
Volume: 20 Issue: 1, 24 - 29, 02.06.2015
Abstract
To compare the effects of different progestins in combined oral contraceptives (COC) on sexual functions and well- being of women. In this prospective and observational study, 52 participants used drosperinone, 48 participants used gestodene, 55 participants used levonorgestrele and 60 participants used non- hormonal contraception. All participants completed the Female Sexual Function Index (FSFI) and Beck Depression Inventory (BDI) at baseline and after six cycles of treatment.
In the hormonal contraception group, there was a statistically significant improvement between FSFI scores at baseline and after six cycles of treatment. In each hormonal contraception subgroup, there was no significant difference between FSFI scores.
In the hormonal contraception group, there was a statistically significant increase between BDI scores at baseline and after six cycles of treatment. In each hormonal contraception subgroup, there was no significant difference between BDI scores. These data show that COC pills make positive effects on female sexuality. Androgenic or antiandrogenic progestins have similar improvements on female sexual function. In addition, COC pills have negative impacts on depression.
References
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- Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561-571.
- Blanco-Molina A, Monreal M. Venousthromboembolism in women taking hormonal contraceptives. Expert Rev Cardiovasc Ther 2010; 8: 211-215.
- Cibula D, Gompel A, Mueck AO, et al. Hormonal contraception and risk of cancer. Hum Reprod Update 2010; 16: 631-650.
- Hannaford PC, Selvaraj S, Elliott AM, et al. Cancer risk amongusers of oral contraceptives: Cohort data from the Royal College of General Practitioner’s Oral ContraceptionStudy. BMJ 2007; 335: 651.
- Hannaford PC, Iversen L, Macfarlane TV, et al. Mortality among contraceptive pill users: cohort evidence from Royal College of General Practitioners' Oral Contraception Study. BMJ 2010; 340: 927.
- Goldstein IMC, Meston CR, Davis SR, et al. Women's sexual function and dysfunction: study, diagnosis and treatment. New York: Taylor & Francis; 2006.
- Bhasin S, Enzlin P, Coviello A, Basson R. Sexual dysfunction in men and women with endocrine disorders. Lancet 2007; 369: 597-611.
- Kurdoglu Z, Usul SY, Tasdemir M, Kurdoglu M. Evaluation of the relationship between endogenous gonadotropins and female sexual function and psychological status in predialysis and hemodialysis patients Gynecol Endocrinol 2012; 28: 336-339.
- Graham CA, Bancroft J, Doll HA, Greco T, Tanner A. Does oral contraceptive-induced reduction in free testosterone adversely affect the sexuality ormood of women? Psychoneuroendocrinology 2007; 32: 246- 255.
- Warnock JK, Clayton A, Croft J, Segraves R, Boggs FC. Comparison of androgens in women with hypoactive sexual desire disorder: those on combined oral contraceptives (COCs) vs. those not on COCs. J Sex Med 2006; 3: 878-882.
- McCoy NL, Matyas JR. Oral contraceptivesandsexuality in universitywomen. Arch Sex Behav 1996; 25: 73-90.
- Caruso S, Agnello C, Intelisano G, et al. Prospective study on sexual behavior of women using 30 microg ethinyl estradiol and 3 mg drospirenone oral contraceptive. Contraception 2005; 72: 19-23.
- Kelly S, Davies E, Fearns S, et al. Effects of oral contraceptives containing ethinyl estradiol with either drospirenone or levonorgestrel on various parameters associated with well-being in healthywomen: A randomized, single-blind, parallel-group, multi centre study. Clin Drug Investig 2010; 30: 325-336.
- Caruso S, Agnello C, Romano M, et al. Preliminary
- study on the effect of four-phasic estradiol valerate and dienogest (E2V/DNG) oral contraceptive on the quality of sexual life. J Sex Med 2011; 8: 2841-2850.
- Oinonen KA, Mazmanian D. To what extent do oral contraceptives influence mood and affect? J Affect Disord 2002; 70: 229-240.
- Joffe H, Cohen LS, Harlow BL. Impact of oral contraceptive pill use on premenstrual mood: predictors of improvement and deterioration. Am J Obstet Gynecol 2003; 189: 1523-1530.
- Ernst U, Baumgartner L, Bauer U, Janssen G. Improvement of quality of life in women using a low- dose desogestrel- containing contraceptive: results of an observational clinical evaluation. Eur J Contracept Reprod Health Care 2002; 7: 238-243.
- Larsson G, Blohm F, Sundell G, Andersch B, Milsom I. A longitudinal study of birth control and pregnancy outcome among women in a Swedish population. Contraception 1997; 56: 9-16.
- Palomba S, Falbo A, Giallauria F, et al. Six weeks of structured exercise training and hypocaloric diet increases the probability of ovulation after clomiphene citrate in over weight and obese patients with polycystic ovary syndrome: a randomized controlled trial. Hum Reprod 2010; 25: 2783-2791.
- Moran LJ, Hutchison SK, Norman RJ, Teede HJ. Life style changes in women with polycystic ovary syndrome. Cochrane Database Syst Rev 2011; 7: CD007506.
- Grady WR, Billy JO, Klepinger DH. Contraceptive method switching in the United States. Perspect Sex Reprod Health 2002; 34: 135-145.
Year 2015,
Volume: 20 Issue: 1, 24 - 29, 02.06.2015
Abstract
References
- Daker-White G. Reliable and valid self-report outcome measures in sexual (dys)function: a systematic review. Arch Sex Behav 2002; 31: 197- 209.
- Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961; 4: 561-571.
- Blanco-Molina A, Monreal M. Venousthromboembolism in women taking hormonal contraceptives. Expert Rev Cardiovasc Ther 2010; 8: 211-215.
- Cibula D, Gompel A, Mueck AO, et al. Hormonal contraception and risk of cancer. Hum Reprod Update 2010; 16: 631-650.
- Hannaford PC, Selvaraj S, Elliott AM, et al. Cancer risk amongusers of oral contraceptives: Cohort data from the Royal College of General Practitioner’s Oral ContraceptionStudy. BMJ 2007; 335: 651.
- Hannaford PC, Iversen L, Macfarlane TV, et al. Mortality among contraceptive pill users: cohort evidence from Royal College of General Practitioners' Oral Contraception Study. BMJ 2010; 340: 927.
- Goldstein IMC, Meston CR, Davis SR, et al. Women's sexual function and dysfunction: study, diagnosis and treatment. New York: Taylor & Francis; 2006.
- Bhasin S, Enzlin P, Coviello A, Basson R. Sexual dysfunction in men and women with endocrine disorders. Lancet 2007; 369: 597-611.
- Kurdoglu Z, Usul SY, Tasdemir M, Kurdoglu M. Evaluation of the relationship between endogenous gonadotropins and female sexual function and psychological status in predialysis and hemodialysis patients Gynecol Endocrinol 2012; 28: 336-339.
- Graham CA, Bancroft J, Doll HA, Greco T, Tanner A. Does oral contraceptive-induced reduction in free testosterone adversely affect the sexuality ormood of women? Psychoneuroendocrinology 2007; 32: 246- 255.
- Warnock JK, Clayton A, Croft J, Segraves R, Boggs FC. Comparison of androgens in women with hypoactive sexual desire disorder: those on combined oral contraceptives (COCs) vs. those not on COCs. J Sex Med 2006; 3: 878-882.
- McCoy NL, Matyas JR. Oral contraceptivesandsexuality in universitywomen. Arch Sex Behav 1996; 25: 73-90.
- Caruso S, Agnello C, Intelisano G, et al. Prospective study on sexual behavior of women using 30 microg ethinyl estradiol and 3 mg drospirenone oral contraceptive. Contraception 2005; 72: 19-23.
- Kelly S, Davies E, Fearns S, et al. Effects of oral contraceptives containing ethinyl estradiol with either drospirenone or levonorgestrel on various parameters associated with well-being in healthywomen: A randomized, single-blind, parallel-group, multi centre study. Clin Drug Investig 2010; 30: 325-336.
- Caruso S, Agnello C, Romano M, et al. Preliminary
- study on the effect of four-phasic estradiol valerate and dienogest (E2V/DNG) oral contraceptive on the quality of sexual life. J Sex Med 2011; 8: 2841-2850.
- Oinonen KA, Mazmanian D. To what extent do oral contraceptives influence mood and affect? J Affect Disord 2002; 70: 229-240.
- Joffe H, Cohen LS, Harlow BL. Impact of oral contraceptive pill use on premenstrual mood: predictors of improvement and deterioration. Am J Obstet Gynecol 2003; 189: 1523-1530.
- Ernst U, Baumgartner L, Bauer U, Janssen G. Improvement of quality of life in women using a low- dose desogestrel- containing contraceptive: results of an observational clinical evaluation. Eur J Contracept Reprod Health Care 2002; 7: 238-243.
- Larsson G, Blohm F, Sundell G, Andersch B, Milsom I. A longitudinal study of birth control and pregnancy outcome among women in a Swedish population. Contraception 1997; 56: 9-16.
- Palomba S, Falbo A, Giallauria F, et al. Six weeks of structured exercise training and hypocaloric diet increases the probability of ovulation after clomiphene citrate in over weight and obese patients with polycystic ovary syndrome: a randomized controlled trial. Hum Reprod 2010; 25: 2783-2791.
- Moran LJ, Hutchison SK, Norman RJ, Teede HJ. Life style changes in women with polycystic ovary syndrome. Cochrane Database Syst Rev 2011; 7: CD007506.
- Grady WR, Billy JO, Klepinger DH. Contraceptive method switching in the United States. Perspect Sex Reprod Health 2002; 34: 135-145.
There are 23 citations in total.
Details
| Primary Language | English |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | June 2, 2015 |
| Published in Issue | Year 2015 Volume: 20 Issue: 1 |