Abstract
Amaç: Yardımcı üreme tekniği (YÜT) sonucu oluşan gebeliklerden doğan ikiz bebeklerin spontan gebelik sonucu olan ikiz bebeklere oranla klinik olarak daha riskli olduğu düşünülmektedir. Ancak YÜT gebelikler sonucunda doğan prematüre bebeklerdeki riskler konusunda bilgiler sınırlıdır. Çalışmamızda YÜT ve spontan gebeliklerden doğan ikiz prematüre bebekler klinik sonuçlar açısından karşılaştırıldı.
Materyal ve metot: Çalışmamıza Eylül 2019 ile Eylül 2020 tarihleri arasında ünitemizde yatan ve 32. gebelik haftası altında doğan tüm ikiz prematüre bebekler dahil edildi. Spontan ve YÜT gebelikler sonucunda doğan prematüre ikiz bebeklerin demografik ve klinik sonuçları karşılaştırıldı.
Bulgular: Çalışmaya spontan ikiz grubunda 116 (81.6%) ve YÜT ikiz grubunda 26 (18.4%) olmak üzere toplam 142 prematüre ikiz dahil edildi. YÜT ve spontan ikiz grupları arasında demografik ve klinik özellikler benzer olarak bulundu (p>0,05).
Sonuç: Çalışmamızda YÜT gebelikler sonucu doğan prematüre bebeklerin spontan olanlara göre ek riske sahip olmadıkları saptandı. Bu sonuç prematürelerde klinik sonuçların ana belirleyicisinin gebelik haftası ve doğum ağırlığı olduğunu göstermektedir.
Supporting Institution
YOK
References
- Özçil MD. İkiz Gebelikler ve Yardımcı Üreme Teknikleri ile Oluşan İkiz Gebeliklerin Feto-maternal Etkilerinin Karşılaştırılması. J Acad Res Med.
- Papiernik E, Zeitlin J, Delmas D, et al. Differences in outcome between twins and singletons born very preterm: results from a population-based European cohort. Hum Reprod.
- Lin D, Li P, Fan D, et al. Association between IVF/ICSI treatment and preterm birth and major perinatal outcomes among dichorionic-diamnionic twin pregnancies: A seven-year retrospective cohort study. Acta Obstet Gynecol Scand.
- Lubchenco LO, Hansman C, Dressler M, Boyd E. Intrauterine Growth as Estimated from Liveborn Birth-Weight Data at 24 to 42 Weeks of Gestation. Pediatrics.
- Wynn JL, Wong HR, Shanley TP, Bizzarro MJ, Saiman L, Polin RA. Time for a neonatal-specific consensus definition for sepsis. Pediatr Crit Care Med.
- Özkan H, Erdeve Ö, Kanmaz Kutman HG. Turkish Neonatal Society guideline on the management of respiratory distress syndrome and surfactant treatment. Turk Pediatri Ars.
- Tayman C, Cakir U, Yucel C, Bekmez BO. Is Endocan a Novel Diagnostic Marker for the Severity of Bronchopulmonary Dysplasia in Very Low Birth Weight Infants? Arch Bronconeumol. International Committee for the Classification of Retinopathy of Prematurity. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol.
- Allan WC, Volpe JJ. Periventricular-intraventricular hemorrhage. Pediatr Clin North Am.
- Bell MJ, Ternberg JL, Feigin RD, et al. Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Ann Surg.
- Cakir U, Tayman C. A Mystery of Patent Ductus Arteriosus and Serum Osmolality in Preterm Infants. Am J Perinatol. Güler AE, Pehlivan H, Korucuoğlu Ü, Çakmak B, Şahin S, Asyalı Biri A. Spontan ve Yardımcı Üreme Tekniği ile Oluşan İkiz Gebeliklerin Perinatal Sonuçları. Gaziosmanpaşa Üniv. Tıp Fak. Derg.
- Yaşar BN, Terzioğlu F. Yardımcı Üreme Tekniklerinde Perinatal Sonuçlar. Anadolu Hemş. ve Sağ. Bil. Derg.
- Mutlu B, Korkmaz A, Yiğit S, Yurdakök M, Tekinalp G. Yardımcı üreme teknolojisi ile doğan bebeklerde Yeni Ballard Skorlaması ile gebelik yaşının belirlenmesi.
- Çakar E, Kavuncuoğlu S, Aldemir EY, Çetinkaya M, Güzeltaş A, Arslan G. Features of multiple pregnancies obtained by in vitro fertilization or spontaneously. Pediatr Int.
- Shevell T, Malone FD, Vidaver J, et al. Assisted reproductive technology and pregnancy outcome. Obstet Gynecol.
- Vasario E, Borgarello V, Bossotti C, et al. IVF twins have similar obstetric and neonatal outcome as spontaneously conceived twins: a prospective follow-up study. Reprod Biomed Online.
- Güney M, Oral B, Mungan T, Ozbasar D. İn vitro fertilizasyon sonrası ikiz gebeliklerin antepartum, intrapartum ve perinatal sonuçları. J Turkish-German Gynecol Assoc.
- Baxi A, Kaushal M. Outcome of twin pregnancies conceived after assisted reproductive techniques. J Hum Reprod Sci. Ramoğlu M, Kavuncuoğlu S, Özbek S, Aldemir E. Kendiliğinden ve in vitro fertilizasyonlu çoğul gebeliklerden erken doğan bebeklerin doğum öncesi ve bedensel büyüme özellikleri. Türk Ped Arş.
- Özkan ZS, Atılgan R, Atlı H, İlhan R, Şimşek M, Sapmaz E. Yardımcı Üreme Teknikleriyle Elde Edilen Çoğul Gebeliklerin Perinatal Akıbeti. J Kartal TR
- Tosun Ö, Yüksel Karatoprak E, Ovalı HF. Yardımcı Üreme Teknikleriyle Oluşan Çoğul Gebeliklerin Değerlendirilmesi ve Postnatal Maliyet Analizi. Anadolu Klin. Tıp Bil. Derg.
- Çağlıyan E, Sarıdaş Demir S, Özmen S, ve ark. İn Vitro Fertilizasyon (IVF) ve Spontan Dikoryonik Diamniotik (DDA) İkiz Gebeliklerinde Obstetrik ve Perinatal Sonuçların Karşılaştırılması. TJRMS. Wang AY, Safi N, Ali F, et al. Neonatal outcomes among twins following assisted reproductive technology: an Australian population-based retrospective cohort study. BMC Pregnancy Childbirth.
- Victora JD, Silveira MF, Tonial CT, et al. Prevalence, mortality and risk factors associated with very low birth weight preterm infants: an analysis of 33 years. J Pediatr (Rio J).
- Chughtai AA, Wang AY, Hilder L, et al. Gestational age-specific perinatal mortality rates for assisted reproductive technology (ART) and other births. Hum Reprod.
- Yarci E, Alyamac Dizdar E, Oncel MY, et al. Successful management of twin anemia/polycythemia sequence by syngeneic partial exchange transfusion. Fetal Diagn Ther.
Abstract
Objectives: It is thought that twin neonates born from pregnancies resulting from assisted reproductive technology (ART) are clinically riskier than twin neonates born from spontaneous pregnancy. However, information on the risks in premature infants born as a result of ART pregnancies is limited. In our study, premature twin infants born from ART and spontaneous pregnancies were compared to clinical outcomes.
Materials and Methods: All premature twin infants hospitalized in our unit between September 2019 and September 2020 and born under 32 weeks of gestation were included in our study. Demographic and clinical results of premature twins born as a result of spontaneous and ART pregnancies were compared.
Results: A total of 142 premature twins, 116 (81.6%) in the spontaneous twin group and 26 (18.4%) in the ART twin group, were included in the study. Demographic and clinical features were similar between ART and spontaneous twin groups (p>0.05).
Conclusion: Our study determined that premature infants born due to ART pregnancies did not have any additional risk compared to spontaneous infants. This result shows that the main determinants of clinical outcomes in premature infants are gestational week and birth weight.
References
- Özçil MD. İkiz Gebelikler ve Yardımcı Üreme Teknikleri ile Oluşan İkiz Gebeliklerin Feto-maternal Etkilerinin Karşılaştırılması. J Acad Res Med.
- Papiernik E, Zeitlin J, Delmas D, et al. Differences in outcome between twins and singletons born very preterm: results from a population-based European cohort. Hum Reprod.
- Lin D, Li P, Fan D, et al. Association between IVF/ICSI treatment and preterm birth and major perinatal outcomes among dichorionic-diamnionic twin pregnancies: A seven-year retrospective cohort study. Acta Obstet Gynecol Scand.
- Lubchenco LO, Hansman C, Dressler M, Boyd E. Intrauterine Growth as Estimated from Liveborn Birth-Weight Data at 24 to 42 Weeks of Gestation. Pediatrics.
- Wynn JL, Wong HR, Shanley TP, Bizzarro MJ, Saiman L, Polin RA. Time for a neonatal-specific consensus definition for sepsis. Pediatr Crit Care Med.
- Özkan H, Erdeve Ö, Kanmaz Kutman HG. Turkish Neonatal Society guideline on the management of respiratory distress syndrome and surfactant treatment. Turk Pediatri Ars.
- Tayman C, Cakir U, Yucel C, Bekmez BO. Is Endocan a Novel Diagnostic Marker for the Severity of Bronchopulmonary Dysplasia in Very Low Birth Weight Infants? Arch Bronconeumol. International Committee for the Classification of Retinopathy of Prematurity. The International Classification of Retinopathy of Prematurity revisited. Arch Ophthalmol.
- Allan WC, Volpe JJ. Periventricular-intraventricular hemorrhage. Pediatr Clin North Am.
- Bell MJ, Ternberg JL, Feigin RD, et al. Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Ann Surg.
- Cakir U, Tayman C. A Mystery of Patent Ductus Arteriosus and Serum Osmolality in Preterm Infants. Am J Perinatol. Güler AE, Pehlivan H, Korucuoğlu Ü, Çakmak B, Şahin S, Asyalı Biri A. Spontan ve Yardımcı Üreme Tekniği ile Oluşan İkiz Gebeliklerin Perinatal Sonuçları. Gaziosmanpaşa Üniv. Tıp Fak. Derg.
- Yaşar BN, Terzioğlu F. Yardımcı Üreme Tekniklerinde Perinatal Sonuçlar. Anadolu Hemş. ve Sağ. Bil. Derg.
- Mutlu B, Korkmaz A, Yiğit S, Yurdakök M, Tekinalp G. Yardımcı üreme teknolojisi ile doğan bebeklerde Yeni Ballard Skorlaması ile gebelik yaşının belirlenmesi.
- Çakar E, Kavuncuoğlu S, Aldemir EY, Çetinkaya M, Güzeltaş A, Arslan G. Features of multiple pregnancies obtained by in vitro fertilization or spontaneously. Pediatr Int.
- Shevell T, Malone FD, Vidaver J, et al. Assisted reproductive technology and pregnancy outcome. Obstet Gynecol.
- Vasario E, Borgarello V, Bossotti C, et al. IVF twins have similar obstetric and neonatal outcome as spontaneously conceived twins: a prospective follow-up study. Reprod Biomed Online.
- Güney M, Oral B, Mungan T, Ozbasar D. İn vitro fertilizasyon sonrası ikiz gebeliklerin antepartum, intrapartum ve perinatal sonuçları. J Turkish-German Gynecol Assoc.
- Baxi A, Kaushal M. Outcome of twin pregnancies conceived after assisted reproductive techniques. J Hum Reprod Sci. Ramoğlu M, Kavuncuoğlu S, Özbek S, Aldemir E. Kendiliğinden ve in vitro fertilizasyonlu çoğul gebeliklerden erken doğan bebeklerin doğum öncesi ve bedensel büyüme özellikleri. Türk Ped Arş.
- Özkan ZS, Atılgan R, Atlı H, İlhan R, Şimşek M, Sapmaz E. Yardımcı Üreme Teknikleriyle Elde Edilen Çoğul Gebeliklerin Perinatal Akıbeti. J Kartal TR
- Tosun Ö, Yüksel Karatoprak E, Ovalı HF. Yardımcı Üreme Teknikleriyle Oluşan Çoğul Gebeliklerin Değerlendirilmesi ve Postnatal Maliyet Analizi. Anadolu Klin. Tıp Bil. Derg.
- Çağlıyan E, Sarıdaş Demir S, Özmen S, ve ark. İn Vitro Fertilizasyon (IVF) ve Spontan Dikoryonik Diamniotik (DDA) İkiz Gebeliklerinde Obstetrik ve Perinatal Sonuçların Karşılaştırılması. TJRMS. Wang AY, Safi N, Ali F, et al. Neonatal outcomes among twins following assisted reproductive technology: an Australian population-based retrospective cohort study. BMC Pregnancy Childbirth.
- Victora JD, Silveira MF, Tonial CT, et al. Prevalence, mortality and risk factors associated with very low birth weight preterm infants: an analysis of 33 years. J Pediatr (Rio J).
- Chughtai AA, Wang AY, Hilder L, et al. Gestational age-specific perinatal mortality rates for assisted reproductive technology (ART) and other births. Hum Reprod.
- Yarci E, Alyamac Dizdar E, Oncel MY, et al. Successful management of twin anemia/polycythemia sequence by syngeneic partial exchange transfusion. Fetal Diagn Ther.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Articles |
| Authors | |
| Publication Date | December 31, 2022 |
| Submission Date | March 24, 2022 |
| Acceptance Date | June 6, 2022 |
| Published in Issue | Year 2022 Volume: 15 Issue: 3 |
Cite
MEU Journal of Health Sciences Assoc was began to the publishing process in 2008 under the supervision of Assoc. Prof. Gönül Aslan, Editor-in-Chief, and affiliated to Mersin University Institute of Health Sciences. In March 2015, Prof. Dr. Caferi Tayyar Şaşmaz undertook the Editor-in Chief position and since then he has been in charge.
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