Abstract
Here, we presented six women with isolated vulvar purpura. No associated lesions such as sclerosis, atrophy, or hypopigmentation were observed. All patients were in postmenopausal period. In this case series, we discussed if a non-blanching purpura could be a component of plasma cell vulvitis or “mucosal porosis”. The possibility of vulvar purpura was questioned as a mucosal equivalent of dermatoporosis which is an age-related degenerative process in the skin. While senile purpura is one of the morphological findings of dermatoporosis, vulvar purpura might be a part of “mucosal porosis”. Rapid response to topical estrogen was remarkable in all patients.
Supporting Institution
NA
Project Number
NA
Thanks
NAzila barahmani
References
- Virgili A, Levratti A, Marzola A, Corazza M. Retrospective histopathologic reevaluation of 18 cases of plasma cell vulvitis. J Reprod Med 2005;50:3-7.
- Virgili A, Corazza M, Minghetti S, Borghi A. Symptoms in plasma cell vulvitis: first observational cohort study on type, frequency and severity. Dermatology 2015;230:113-8.
- Li Q, Leopold K, Carlson JA. Chronic vulvar purpura: persistent pigmented purpuric dermatitis (lichen aureus) of the vulva or plasma cell (Zoon’s) vulvitis? J Cutan Pathol 2003;30:572-6.
- Kato T, Kuramoto Y, Tadaki T, Hashimoto K, Tagami H. Chronic vulvar purpura. Dermatologica 1990;180:174-6.
- Kaya G, Saurat JH. Dermatoporosis: a chronic cutaneous insufficiency/fragility syndrome. Dermatology 2007;215:284-94.
- Weyers W, Ende Y, Schalla W, Diaz-Cascajo C. Balanitis of Zoon: a clinicopathologic study of 45 cases. Am J Dermatopathol 2002;24:459-67.
- Virgili A, Borghi A, Minghetti S, Corazza M. Comparative study on topical immunomodulatory and anti-inflammatory treatments for plasma cell vulvitis: long-term efficacy and safety. J Eur Acad Dermatol Venereol 2015;29:507-14.
- Kim HK, Kang SY, Chung YJ, Kim JH, Kim MR. The recent review of the genitourinary syndrome of menopause. J Menopausal Med 2015;21:65-71.
- Phillips NA, Bachmann GA. The genitourinary syndrome of menopause. Menopause 2021;28:579-88.
Abstract
Bu yazıda, izole vulvar purpurası olan altı hastayı sunduk. Hiçbir hastada eşlik eden skleroz, atrofi ya da hipopigmentasyon gibi bulgular gözlenmedi. Hastaların tümü postmenopozal dönemde idi. Bu vaka serisinde, vulvada görülen purpurik lezyonların plazma hücreli vulvitin bir komponenti ya da yeni bir antite “mukozal poroz” olma olasılığını tartıştık. Vulvada görülen purpuranın, yaşlanmaya bağlı olarak deride tanımlanan dermatoporozun “mukozal” eşdeğeri olabileceği fikri ilginç olabilir. Senil purpura, dermatoporozun morfolojik bir bulgusu ise, belki de vulvar purpura mukozal porozun bir göstergesidir. Tüm hastalarda topikal östrojenle hızlı bir düzelme gözlenmesi bu teoriyi destekler niteliktedir.
Keywords
dermatoporoz mukoza plazma hücreli vulvit poroz purpura vulva
Project Number
NA
References
- Virgili A, Levratti A, Marzola A, Corazza M. Retrospective histopathologic reevaluation of 18 cases of plasma cell vulvitis. J Reprod Med 2005;50:3-7.
- Virgili A, Corazza M, Minghetti S, Borghi A. Symptoms in plasma cell vulvitis: first observational cohort study on type, frequency and severity. Dermatology 2015;230:113-8.
- Li Q, Leopold K, Carlson JA. Chronic vulvar purpura: persistent pigmented purpuric dermatitis (lichen aureus) of the vulva or plasma cell (Zoon’s) vulvitis? J Cutan Pathol 2003;30:572-6.
- Kato T, Kuramoto Y, Tadaki T, Hashimoto K, Tagami H. Chronic vulvar purpura. Dermatologica 1990;180:174-6.
- Kaya G, Saurat JH. Dermatoporosis: a chronic cutaneous insufficiency/fragility syndrome. Dermatology 2007;215:284-94.
- Weyers W, Ende Y, Schalla W, Diaz-Cascajo C. Balanitis of Zoon: a clinicopathologic study of 45 cases. Am J Dermatopathol 2002;24:459-67.
- Virgili A, Borghi A, Minghetti S, Corazza M. Comparative study on topical immunomodulatory and anti-inflammatory treatments for plasma cell vulvitis: long-term efficacy and safety. J Eur Acad Dermatol Venereol 2015;29:507-14.
- Kim HK, Kang SY, Chung YJ, Kim JH, Kim MR. The recent review of the genitourinary syndrome of menopause. J Menopausal Med 2015;21:65-71.
- Phillips NA, Bachmann GA. The genitourinary syndrome of menopause. Menopause 2021;28:579-88.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Case Reports |
| Authors | |
| Project Number | NA |
| Publication Date | May 31, 2022 |
| Published in Issue | Year 2022 Volume: 5 Issue: 1 |
