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Irritable bowel syndrome: Prevalence and associated factors in a faculty of medicine in Southeast of Turkey

Year 2021, Volume: 15 Issue: 4, 655 - 660, 20.12.2021
https://doi.org/10.21763/tjfmpc.970954

Abstract

Objective: Irritable bowel syndrome (IBS) is one of the most common gastrointestinal diseases that reduce people's quality of life and work efficiency. Studies on the prevalence of IBS in Turkey are scarce. This study aims to determine IBS prevalence and related factors among medical students in Gaziantep. Methods: The cross-sectional study was conducted at February 2021. Data were collected from students of Gaziantep University Faculty of Medicine via online questionnaire. IBS symptoms were evaluated by using the Rome IV diagnostic criteria. Results: A total of 427 (171 preclinical, 256 clinical) students were examined. The average age of the participants was 22.07 ±2.55 years and 58.1% of them were women. Sixty-nine (16.2%) students had symptoms consistent with a diagnosis of IBS. The IBS prevalence was 16.9% (n=42) among the female students and 15.1% (n=27) among the male students. The prevalence in clinical classes was 19.5% and was significantly higher than preclinical classes (11.1% p=0.021). There was a significant difference between IBS and positive family history OR: 2.57 (95% CI: 1.39-4.75), food intolerance OR: 4.14 (95% CI: 2.36-7.27), frequent sleep problems OR: 2.16 (95% CI: 1.24-3.75), not exercising regularly OR: 1.71 (95% CI: 1.01-2.91). There was not a statistically significant relationship between IBS and income, body mass index, smoking and emotional stress. Conclusion: The general prevalence was 16.2%, and it was 19.5% in clinical classes. The factors of having IBS in family history, food intolerance, sleep problems and not exercising regularly can be associated with the prevalence of IBS.

References

  • 1. Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA 2015;313(9):949-958.
  • 2. Defrees DN, Bailey J. Irritable Bowel Syndrome: Epidemiology, Pathophysiology, Diagnosis, and Treatment. Prim Care 2017;44(4):655-671.
  • 3. Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol 2012;10(7):712-721.e4.
  • 4. Shorey S, Demutska A, Chan V, Siah KTH. Adults living with irritable bowel syndrome (IBS): A qualitative systematic review. J Psychosom Res 2021;140:110289.
  • 5. Enck P, Aziz Q, Barbara G, Farmer AD, Fukudo S, Mayer EA, et al. Irritable bowel syndrome. Nat Rev Dis Primers 2016; 2: 16014.
  • 6. Stanghellini V. Functional Dyspepsia and Irritable Bowel Syndrome: Beyond Rome IV. Dig Dis 2017;35:14-17.
  • 7. Pacheco RL, Roizenblatt A, Góis AFT, Latorraca COC, Mota CFMGP, Riera R. What do Cochrane systematic reviews say about the management of irritable bowel syndrome? Sao Paulo Med J 2019 May 8;137(1):82-91.
  • 8. Elhosseiny D, MahmoudNE, Manzour AF. Factors associated with irritable bowel syndrome among medical students in Ain Shams University. Journal of the Egyptian Public Health Association 2019;94(1): 23.
  • 9. Alaqeel MK, Alowaimer NA, Alonezan AF, Almegbel NY. Alaujan, FY. Prevalence of Irritable Bowel Syndrome and its Association with Anxiety among Medical Students at King Saud bin Abdulaziz University for Health Sciences in Riyadh. Pak J Med Sci 2017;33(1):33–36.
  • 10. Seger S, Nasharuddin NNB, Fernandez SL, Yunus SRBM, Shun NTM, Agarwal P, et al. Prevalence and factors associated with irritable bowel syndrome among medical students in a Malaysian private university: a cross sectional study. Pan Afr Med J 2020;37:151.
  • 11. Ibrahim NK. A systematic review of the prevalence and risk factors of irritable bowel syndrome among medical students. Turk J Gastroenterol 2016;27(1):10–16.
  • 12. Hendren NS, de Lemos JA, Ayers C, Das SR, Rao A, Carter S, et al. Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19: Results From the American Heart Association COVID-19 Cardiovascular Disease Registry. Circulation 2021;143(2):135-144.
  • 13. Lacy BE, Patel NK. Rome Criteria and a Diagnostic Approach to Irritable Bowel Syndrome. J Clin Med 2017; 6(11): 99.
  • 14. Baysoy G, Güler-Baysoy N, Kesicioğlu A, Akın D, Dündar T, Pamukçu-Uyan A. Prevalence of irritablebowelsyndrome in adolescents in Turkey: effects of gender, lifestyle and psychological factors. Turk J Pediatr 2014;56(6):604-611.
  • 15. Oka P, Parr H, Barberio B, Black CJ, Savarino EV, Ford AC. Global prevalence of irritable bowel syndromea ccordingto Rome III or IV criteria: a systematic review and meta- analysis. Lancet Gastroenterol Hepatol 2020;5(10) :908-917.
  • 16. Vasquez-Rios G, Machicado JD, Ticse R, Ruiz EF, Gamero MT, Pezua A, et al. Stressand a sedentary lifestyle are associated with irritable bowel syndrome in medical students from Peru: a cross-sectional study. Eur J Gastroenterol Hepatol 2019;31(11):1322-1327.
  • 17. Liu Y, Liu L, Yang Y, He Y, Zhang Y, Chen S, et al. A school-basedstudy of irritable bowel syndrome in medical students in beijing, china: prevalence and some related factors. Gastroenterol Res Pract 2014; 2014:124261.
  • 18. Sehonou J, Dodo LRS. Clinical profile and factors associated with irritable bowel syndrome among medical students in Cotonou (Benin). Pan Afr Med J 2018;31:123.
  • 19. AlButaysh OF, AlQuraini AA, Almukhaitah AA, Alahmdi YM, Alharbi FS. Epidemiology of irritable bowel syndrome and its associatedf actors in Saudi undergraduate students. Saudi J Gastroenterol 2020;26(2):89-93.
  • 20. Ibrahim NK., Battarjee WF, Almehmadi SA. Prevalence and predictors of irritable bowel syndrome among medical students and interns in King Abdulaziz University, Jeddah. The Libyan J Med 2013; 8: 21287
  • 21. Okami Y, Kato T, Nin G, Harada K, Aoi W, Wada S, et al. Lifestyle and psychological factors related to irritable bowel syndrome in nursing and medical school students. J Gastroenterol 2011;46(12):1403-1410.
  • 22. Wang Y, Jin F, Chi B, Duan S, Zhang Q, Liu Y, et al. Gender differences in irritable bowel syndrome among medical students at Inner Mongolia Medical University, China: a cross-sectional study. Psychol Health Med 2016;21(8):964-974.
  • 23. Ranjbaran Z, Keefer L, Farhadi A, Stepanski E, Sedghi S, Keshavarzian A. Impact of sleep disturbances in inflammatory bowel disease. J Gastroenterol Hepatol 2007;22(11):1748-1753.
  • 24. Camilleri M. Management Options for Irritable Bowel Syndrome. Mayo Clinic proceedings 2018; 93(12): 1858–1872.
  • 25. Basandra S, Bajaj D. Epidemiology of Dyspepsia and Irritable Bowel Syndrome (IBS) in Medical Students of Northern India. J Clin Diagn Res 2014; 8: JC13-6.
  • 26. Monsbakken KW, Vandvik PO, Farup PG. Perceived food intolerance in subjects with irritable bowel syndrome-- etiology, prevalence and consequences. Eur J Clin Nutr 2006;60:667–672.
  • 27. Hakami RM, Elmakki E, Hasanain T, Alnami A, Khawaji A, Ali L, et.al. Irritable Bowel Syndrome: assessment of prevalence and risk factors in Saudi University students using Rome IV Criteria. Gastroenterology Insights 2019;10(1):10-16.

İrritabl barsak sendromu: Türkiye’nin güneyinde bir tıp fakültesinde prevalans ve ilişkili faktörler

Year 2021, Volume: 15 Issue: 4, 655 - 660, 20.12.2021
https://doi.org/10.21763/tjfmpc.970954

Abstract

Amaç: İrritabl barsak sendromu (İBS) kişilerin yaşam kalitesini ve çalışma verimini azaltan dünya çapında en sık görülen gastrointestinal hastalıklardan birisidir. Türkiye'de İBS prevalansı ile ilgili sınırlı sayıda çalışma vardır. Bu çalışma Tıp Fakültesi öğrencilerinde IBS prevalansını ve ilişkili faktörleri belirlemek amacıyla yapılmıştır. Yöntem: Kesitsel çalışma 2021 Şubat ayında gerçekleştirildi. Gaziantep Üniversitesi Tıp Fakültesi öğrencilerinden online anket aracılığıyla veriler toplandı. IBS semptomları, Roma IV tanı kriterleri kullanılarak değerlendirildi. Bulgular: Toplam 427 (171 preklinik, 256 klinik) öğrenci analiz edildi. Katılımcıların yaş ortalaması 22,07 ±2,55 yıl, %58,1’i kadındı. İBS prevalansı %16,2 (Kız öğrenciler için %16,9 (n=42), erkek öğrenciler için %15,1 (n=27) p=0,608) olarak bulundu. Klinik sınıflarda prevalans %19,5 (n=50) olup preklinik sınıflara göre (%11,1 n=19) anlamlı olarak yüksekti (p=0,021). Ailede İBS öyküsü olması OR:2,57 (%95 CI:1,39-4,75), gıda intoleransı OR:4,14 (%95 CI:2,36-7,27), sık uyku problemleri olması OR:2,16 (%95 CI:1,24-3,75), düzenli egzersiz yapmama OR:1,71 (%95CI: 1,01-2,91) ile İBS arasında anlamlı ilişki bulundu. Beden kitle indexi, sigara, gelir durumu, geçmişte büyük üzüntü verici olay yaşama ile İBS arasında anlamlı ilişki bulunmadı (p>0,05). Sonuç: Genel prevalans %16,2 olup klinik sınıflarda %19,5 bulunmuştur. Ailede İBS öyküsü, gıda intoleransı, uyku problemleri ve düzenli egzersiz yapmama İBS prevalansı ile ilişkilidir.

References

  • 1. Chey WD, Kurlander J, Eswaran S. Irritable bowel syndrome: a clinical review. JAMA 2015;313(9):949-958.
  • 2. Defrees DN, Bailey J. Irritable Bowel Syndrome: Epidemiology, Pathophysiology, Diagnosis, and Treatment. Prim Care 2017;44(4):655-671.
  • 3. Lovell RM, Ford AC. Global prevalence of and risk factors for irritable bowel syndrome: a meta-analysis. Clin Gastroenterol Hepatol 2012;10(7):712-721.e4.
  • 4. Shorey S, Demutska A, Chan V, Siah KTH. Adults living with irritable bowel syndrome (IBS): A qualitative systematic review. J Psychosom Res 2021;140:110289.
  • 5. Enck P, Aziz Q, Barbara G, Farmer AD, Fukudo S, Mayer EA, et al. Irritable bowel syndrome. Nat Rev Dis Primers 2016; 2: 16014.
  • 6. Stanghellini V. Functional Dyspepsia and Irritable Bowel Syndrome: Beyond Rome IV. Dig Dis 2017;35:14-17.
  • 7. Pacheco RL, Roizenblatt A, Góis AFT, Latorraca COC, Mota CFMGP, Riera R. What do Cochrane systematic reviews say about the management of irritable bowel syndrome? Sao Paulo Med J 2019 May 8;137(1):82-91.
  • 8. Elhosseiny D, MahmoudNE, Manzour AF. Factors associated with irritable bowel syndrome among medical students in Ain Shams University. Journal of the Egyptian Public Health Association 2019;94(1): 23.
  • 9. Alaqeel MK, Alowaimer NA, Alonezan AF, Almegbel NY. Alaujan, FY. Prevalence of Irritable Bowel Syndrome and its Association with Anxiety among Medical Students at King Saud bin Abdulaziz University for Health Sciences in Riyadh. Pak J Med Sci 2017;33(1):33–36.
  • 10. Seger S, Nasharuddin NNB, Fernandez SL, Yunus SRBM, Shun NTM, Agarwal P, et al. Prevalence and factors associated with irritable bowel syndrome among medical students in a Malaysian private university: a cross sectional study. Pan Afr Med J 2020;37:151.
  • 11. Ibrahim NK. A systematic review of the prevalence and risk factors of irritable bowel syndrome among medical students. Turk J Gastroenterol 2016;27(1):10–16.
  • 12. Hendren NS, de Lemos JA, Ayers C, Das SR, Rao A, Carter S, et al. Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19: Results From the American Heart Association COVID-19 Cardiovascular Disease Registry. Circulation 2021;143(2):135-144.
  • 13. Lacy BE, Patel NK. Rome Criteria and a Diagnostic Approach to Irritable Bowel Syndrome. J Clin Med 2017; 6(11): 99.
  • 14. Baysoy G, Güler-Baysoy N, Kesicioğlu A, Akın D, Dündar T, Pamukçu-Uyan A. Prevalence of irritablebowelsyndrome in adolescents in Turkey: effects of gender, lifestyle and psychological factors. Turk J Pediatr 2014;56(6):604-611.
  • 15. Oka P, Parr H, Barberio B, Black CJ, Savarino EV, Ford AC. Global prevalence of irritable bowel syndromea ccordingto Rome III or IV criteria: a systematic review and meta- analysis. Lancet Gastroenterol Hepatol 2020;5(10) :908-917.
  • 16. Vasquez-Rios G, Machicado JD, Ticse R, Ruiz EF, Gamero MT, Pezua A, et al. Stressand a sedentary lifestyle are associated with irritable bowel syndrome in medical students from Peru: a cross-sectional study. Eur J Gastroenterol Hepatol 2019;31(11):1322-1327.
  • 17. Liu Y, Liu L, Yang Y, He Y, Zhang Y, Chen S, et al. A school-basedstudy of irritable bowel syndrome in medical students in beijing, china: prevalence and some related factors. Gastroenterol Res Pract 2014; 2014:124261.
  • 18. Sehonou J, Dodo LRS. Clinical profile and factors associated with irritable bowel syndrome among medical students in Cotonou (Benin). Pan Afr Med J 2018;31:123.
  • 19. AlButaysh OF, AlQuraini AA, Almukhaitah AA, Alahmdi YM, Alharbi FS. Epidemiology of irritable bowel syndrome and its associatedf actors in Saudi undergraduate students. Saudi J Gastroenterol 2020;26(2):89-93.
  • 20. Ibrahim NK., Battarjee WF, Almehmadi SA. Prevalence and predictors of irritable bowel syndrome among medical students and interns in King Abdulaziz University, Jeddah. The Libyan J Med 2013; 8: 21287
  • 21. Okami Y, Kato T, Nin G, Harada K, Aoi W, Wada S, et al. Lifestyle and psychological factors related to irritable bowel syndrome in nursing and medical school students. J Gastroenterol 2011;46(12):1403-1410.
  • 22. Wang Y, Jin F, Chi B, Duan S, Zhang Q, Liu Y, et al. Gender differences in irritable bowel syndrome among medical students at Inner Mongolia Medical University, China: a cross-sectional study. Psychol Health Med 2016;21(8):964-974.
  • 23. Ranjbaran Z, Keefer L, Farhadi A, Stepanski E, Sedghi S, Keshavarzian A. Impact of sleep disturbances in inflammatory bowel disease. J Gastroenterol Hepatol 2007;22(11):1748-1753.
  • 24. Camilleri M. Management Options for Irritable Bowel Syndrome. Mayo Clinic proceedings 2018; 93(12): 1858–1872.
  • 25. Basandra S, Bajaj D. Epidemiology of Dyspepsia and Irritable Bowel Syndrome (IBS) in Medical Students of Northern India. J Clin Diagn Res 2014; 8: JC13-6.
  • 26. Monsbakken KW, Vandvik PO, Farup PG. Perceived food intolerance in subjects with irritable bowel syndrome-- etiology, prevalence and consequences. Eur J Clin Nutr 2006;60:667–672.
  • 27. Hakami RM, Elmakki E, Hasanain T, Alnami A, Khawaji A, Ali L, et.al. Irritable Bowel Syndrome: assessment of prevalence and risk factors in Saudi University students using Rome IV Criteria. Gastroenterology Insights 2019;10(1):10-16.
There are 27 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Orijinal Articles
Authors

Hatice Tuba Akbayram 0000-0002-9777-9596

Publication Date December 20, 2021
Submission Date July 13, 2021
Published in Issue Year 2021 Volume: 15 Issue: 4

Cite

Vancouver Akbayram HT. Irritable bowel syndrome: Prevalence and associated factors in a faculty of medicine in Southeast of Turkey. TJFMPC. 2021;15(4):655-60.

English or Turkish manuscripts from authors with new knowledge to contribute to understanding and improving health and primary care are welcome.